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. 2021 Nov 22;11(59):37413–37425. doi: 10.1039/d1ra06283b

Skin irritation studies of E-SLNs using Draize scoring.

Groups Erythema score Edema score P.D.I. PDII
1 h 12 h 24 h 1 h 12 h 24 h 1 h 12 h 24 h
Negative control 0 0 0 0 0 0 0 0 0 0
Positive control 1 3 3 1 1 2 1 4 5 3.33
E-SLN loaded hydrogel 0 1 0 0 0 0 0 1 0 0.33