Skin irritation studies of E-SLNs using Draize scoring.
Groups | Erythema score | Edema score | P.D.I. | PDII | ||||||
---|---|---|---|---|---|---|---|---|---|---|
1 h | 12 h | 24 h | 1 h | 12 h | 24 h | 1 h | 12 h | 24 h | ||
Negative control | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Positive control | 1 | 3 | 3 | 1 | 1 | 2 | 1 | 4 | 5 | 3.33 |
E-SLN loaded hydrogel | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0.33 |