IC₅₀ values of the tested compounds against various human cancer/normal cell lines.

Comp.	IC50 (μM)
	HeLa	MCF-7	HepG2	SCC-15	HUVEC	293T
12e	4.056 ± 0.316	17.50 ± 2.320	42.58 ± 3.810	2.209 ± 0.314	90.38 ± 4.720	>100
12a	0.173 ± 0.031	0.681 ± 0.048	0.434 ± 0.038	0.148 ± 0.027	5.596 ± 0.375	2.037 ± 0.091
12b	0.030 ± 0.005	0.110 ± 0.014	0.043 ± 0.007	0.028 ± 0.006	0.416 ± 0.039	0.616 ± 0.051
12c	0.092 ± 0.009	0.858 ± 0.088	1.307 ± 0.091	0.264 ± 0.027	2.504 ± 0.233	5.310 ± 0.486
12d	0.064 ± 0.005	0.095 ± 0.008	0.402 ± 0.035	0.078 ± 0.002	1.816 ± 0.118	0.974 ± 0.112
13a	0.974 ± 0.081	5.771 ± 0.438	4.288 ± 0.381	0.786 ± 0.081	11.40 ± 0.548	>100
13b	0.096 ± 0.009	0.140 ± 0.018	0.535 ± 0.036	0.154 ± 0.015	1.218 ± 0.150	0.409 ± 0.037
13c	0.116 ± 0.006	1.734 ± 0.201	7.091 ± 0.661	3.251 ± 0.220	28.39 ± 3.110	>100
14b	0.112 ± 0.008	0.182 ± 0.017	0.993 ± 0.004	0.228 ± 0.004	3.810 ± 0.287	7.854 ± 0.417
15a	0.230 ± 0.004	2.031 ± 0.073	5.080 ± 0.318	0.722 ± 0.029	6.772 ± 0.315	22.60 ± 1.180
15b	0.064 ± 0.005	0.029 ± 0.001	0.390 ± 0.013	0.015 ± 0.002	1.055 ± 0.048	2.629 ± 0.151
Rigosertib	0.065 ± 0.005	0.022 ± 0.003	0.108 ± 0.017	0.035 ± 0.003	0.122 ± 0.015	0.036 ± 0.013