The IC50 ± SD (μM) valuesa in various cell lines for the synthesized complexes.
| Compound | MCF-7 | MDA-MD-231 | HT-29 | HeLa | Neuro-2a | L929 |
|---|---|---|---|---|---|---|
| 1 | 56.6 ± 7.78 | 28.9 ± 2.47 | 57.9 ± 4.71 | 39.2 ± 2.98 | 79.5 ± 8.44 | >100 |
| 2 | 15.6 ± 3.24 | 5.94 ± 1.98 | 17.3 ± 2.57 | 41.2 ± 5.07 | 81.2 ± 9.28 | >100 |
| 3 | 17.9 ± 2.66 | 9.18 ± 2.25 | 14.6 ± 3.55 | 37.6 ± 4.61 | 87.7 ± 6.93 | >100 |
| H2pydco | 57.9 ± 5.33 | 45.7 ± 4.75 | 58.9 ± 5.01 | 67.1 ± 5.45 | >100 | >100 |
| bpy | 51.3 ± 4.78 | 24.9 ± 1.98 | 67.8 ± 5.54 | 46.5 ± 4.03 | 97.3 ± 8.70 | >100 |
| Cisplatin | 5.94 ± 1.47 | 24.7 ± 4.71 | 19.3 ± 3.46 | 0.45 ± 0.13 | 103 ± 9.8 | 0.7 ± 0.2 |
The concentration of the complex required to inhibit cell growth by 50%. The experiments were done in triplicate. Data were expressed as the mean of the triplicate. IC50 > 100 μM is considered to be inactive.