Table 1.
Demographics and ocular characteristics of multiple sclerosis and healthy controls.
| Characteristics | Healthy controls (n = 84 participants, 149 eyes) | Multiple sclerosis (n = 74 participants, 129 eyes) | P value |
|---|---|---|---|
| Age | 39 ± 12 | 42 ± 11 | 0.128 |
| Gender, female | 54, 64% | 49, 66% | 0.799 |
| Diabetes, no | 84, 100% | 74, 100% | – |
| Hypertension, no | 74, 88% | 71, 96% | 0.087 |
| Visual acuity, logMAR value (Snellen) | 0.01 ± 0.02 (6/6-1) | 0.01 ± 0.03 (6/6-1) | 0.160 |
| Intraocular pressure, mmHg | 15.40 ± 2.60 | 17.57 ± 2.96 | <0.001 |
| Signal strength, peripapillary | 8.49 ± 0.90 | 8.63 ± 0.92 | 0.207 |
| Signal strength, macular | 9.07 ± 0.91 | 9.22 ± 1.03 | 0.196 |
| Optic disc area, mm2 | 1.83 ± 0.33 | 1.82 ± 0.27 | 0.710 |
| Optic disc ratio | 1.10 ± 0.05 | 1.10 ± 0.06 | 0.433 |
| Optic disc orientation, degrees | 103.14 ± 28.78 | 98.93 ± 27.91 | 0.219 |
| Fovea distance, µm | 4.45 ± 0.24 | 4.49 ± 0.26 | 0.224 |
| Fovea angle, degrees | −6.73 ± 2.96 | −7.12 ± 3.40 | 0.310 |
| Refractive error, dioptres | −0.14 ± 2.00 | 0.07 ± 1.35 | 0.319 |
Data presented are mean (SD) or number (%), as appropriate.
P value was obtained with independent t-test or Kruskal-Wallis for the continuous variables and with chi-square or Fisher's exact tests for categorical variables.