Fig. 5.

A filled structure (PDB ID 7CH5) showing the “backside” of SARS-CoV-2 RBD (rotated 180° from Fig. 4) and the epitopes for antibodies S2H97 (green; [261]) and 6D6/7D6 (yellow; [432]). A small portion of the ACE2 binding site (white) can be seen peaking around the edge. The S2H97 and 7D6 epitopes are based on the structures shown in PDB IDs 7M7W and 7EAM, respectively. The area denoted by the red circle indicates the area in which the epitopes overlap. The PDB program [201, 202] was used to generate and annotate the structures. ACE2 angiotensin-converting enzyme-2, PDB Protein Data Bank