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. 2022 Apr 19;6(8):2517–2519. doi: 10.1182/bloodadvances.2021006044

Table 2.

Summary of the frequency of PNH clones detection in patients with IBMFS according to previous studies

Study Disease (n) Patients with IBMFS who have a PNH clone Cutoff value Year
Keller et al6 SDS (3), SDS likely (16), SDS possible (7) 0/26 Red cells >1.0%
Neutrophils >1.0%
DeZern et al4 DC (9), FA (4), DBA (2), SDS (3), c-MPL (2) 0/20 0.1% 2000-2008
0.01% 2009-2014
Shah et al1 DC (3), FA (2), DBA (1), Others (3) 0/9 Granulocytes >1.0% 2010-2018
Erythrocytes >1.0% 2010-2018
Granulocytes >0.05% 2018-2020
Monocytes >0.3% 2018-2020
Erythrocytes >0.01% 2018-2020
Our data DC (8), FA (9), DBA (3), SDS (1) 9/21 Granulocytes >0.020%
Erythrocytes >0.037%

DBA, Diamond–Blackfan anemia.