ANOVA of the fitted polynomial quadratic model.

Source	Sum of squares	df	Mean square	F value	p-Valuea	Significanceb
Model	3.845	9	0.427	20.97	0.0003	***
A	0.162	1	0.162	7.97	0.0256	*
B	0.349	1	0.349	17.11	0.0044	**
C	2.112 × 10−3	1	2.112 × 10−3	0.10	0.7568	—
AB	0.116	1	0.116	5.67	0.0487	*
AC	0.026	1	0.026	1.26	0.2993	—
BC	0.391	1	0.391	19.18	0.0032	***
A2	1.622	1	1.622	79.65	<0.0001	***
B2	0.668	1	0.668	32.78	0.0007	***
C2	0.259	1	0.259	12.74	0.0091	***
Residual	0.143	7	0.020	—	—	—
Lack of fit	0.110	3	0.037	4.44	0.0919	—
Pure error	0.033	4	8.230 × 10−3	—	—	—
Cor total	3.988	16	—	—	—	—
R 2	0.9642		Adj R2	0.9183		C.V.% = 1.83

^aSource: ANOVA using design-expert 8.0.6.

^b*Significant at 0.01 < p < 0.05, **significant at p < 0.01, and ***significant at p < 0.001.