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. 2022 Jan 31;71(5):1023–1033. doi: 10.2337/db21-0574

Figure 5.

Figure 5

Overexpression of FGF19 reverses hyperglycemia induced by JQ-1. A: Experimental protocol. GTT, glucose tolerance test; ip, intraperitoneal. B: Plasma FGF19 levels in AAV-GFP– and AAV-FGF19–treated mice. C: Body weight in AAV-GFP– and AAV-FGF19–treated mice during JQ-1 treatment. Blood glucose levels (D) and AUC (E) during ipGTT (day10). F: Plasma insulin levels during ipGTT. Data are expressed as means ± SEM. *P < 0.05, **P < 0.01 vs. AAV-GFP–treated mice (n = 9–10). N.D., not detected.