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. 2022 Feb 8;71(5):1137–1148. doi: 10.2337/db21-0839

Figure 2.

Figure 2

Heritability estimates and SEs of diabetes complications using the ACCORD data. A: Estimates from genotype and imputed data are obtained using the GREML-SC and GREML-LDMS-I approaches, respectively. We adjusted for sex, age at baseline, CVD history at baseline, and the top five genetic principal components. B: GREML-LDMS estimates with eight bins (two LD bins for each of the four MAF bins). For each phenotype, the sum of estimates from the eight bins of MAF shown in panel B is equal to the estimate represented as the green bar on panel A.