Figure 4.

Unsupervised clustering of 760 transcripts reveals a low-risk patient group with a high expression of T cell-related transcripts

Heatmap of gene expression displays a high expression of transcripts in column cluster 4 in a subset of patients without death and/or recurrence. ORA of transcripts in this cluster revealed that cluster 4 was significantly enriched for multiple biological processes related to adaptive immunity. Patients in the high-risk patient cluster who had a lower expression of cluster 4 transcripts displayed an increased risk of death and/or recurrence (HR = 3.703, 95% CI 0.905–15.15, Log rank p = 0.069).