Skip to main content
. 2022 Apr 11;14(2):130–139. doi: 10.5114/jcb.2022.115379

Table 3.

Literature review. Selected studies of eye plaque brachytherapy for uveal melanoma utilizing intra- operative ultrasound (IOUS) guidance for plaque placement

Series Brachytherapy modality Institution Study period Patients Follow-up (months) Local control rate Distant metastasis rate
Wong et al. (2022) 125I Houston Methodist Hospital 2013-2019 180 Median: 30.8 Mean: 37.3
Range: 12.2-96.3
100.0% 12.2%
Aziz et al. (2017) 125I, 106Ru Cleveland Clinic 2004-2013 252 (198 with IOUS guidance) Mean: 30.9 98.5% N.R.
Bellerive et al. (2017) 125I, 106Ru Cleveland Clinic 2004-2014 374 (316 with IOUS guidance) Median: 47.0
Range: 12.0-156.0
93.4% at 5 y (act) N.R.
Badiyan et al. (2014) 125I Washington University SOM, St. Louis 1996-2011 526 Median: 45.9 Mean: 53.4
Range: 6.0-175.0
97.3% at 3 y (act)
95.4% at 5 y (act)
N.R.
Chang et al. (2012) 125I University of California, Los Angeles 2007-2011 150 Mean: 21.5
Range: 6.0-48.0
100% 6%
Tabandeh et al. (2000) 125I University of Miami SOM 1992-1998 117 Mean: 37.0
Range: 2.0-64.0
98.3% 0%