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. 2022 Apr 11;14(2):130–139. doi: 10.5114/jcb.2022.115379

Table 4.

Literature review. Selected studies reporting long-term outcomes for uveal melanoma treated with 125I eye plaque brachytherapy

Series Brachytherapy modality Institution Study date Patients Follow-up (months) Local control rate Distant metastasis rate
Le et al. (2018) 125I University of Southern California 1990-2015 133 Median: 42.0
Range: 0.0-171.0
98.3% at 5 y (act) 10.3%
Miguel et al. (2018) 125I Hospital Universitario de Valladolid, Spain 1996-2016 243 Median: 73.9
Range: 3.0-202.0
96% at 3 y
94% at 5 y
93% at 10 y
73% at 15 y
N.R.
Wisely et al. (2016) 125I Ohio State University 1994-2009 113 Median: 65.5
Range: 2.0-180.0
93% at 5 y N.R.
Wagner et al. (2014) 125I University of Utah 1996-2011 107 (88 with follow-up data) Median: 48.9
Range: 1.0-156.0
94% at 5 y
94% at 10 y
5% at 5 y
11% at 10 y
Correa et al. (2009) 125I Catalan Institute of Oncology, Spain 1996-2004 120 Median: 50.4
Range: 3.2-100.7
95.3% at 2 y
88.4% at 5 y
Jensen et al. (2005) 125I Mayo Rochester 1986-2000 156 Median: 74.0
Range: 7.0-225.0
92% at 5 y 10% at 5 y
27% at 10 y
Lumbroso- Le Rouic et al. (2004) 125I Institute Curie, Paris, France 1990-2000 136 Median: 62.0
Range: 13.0-128.0
98.5% 4% at 5 y
Nag et al. (2003) 125I Ohio State University 1989-1998 78 Median: 49.0
Range: 8.0-112.0
95% N.R.
Jones et al. (2000) 125I Medical College of Wisconsin 1987-1994 63 Median: 36.0 86.9% at 3 y N.R.
Sia et al. (2000) 125I Sir Charles Gairdner Hospital 1985-1997 49 Mean: 39.5 80% at 5 y N.R.
Quivey et al. (1996) 125I Wills Eye Hospital 1982-1990 150 Median: 68.0 81% at 5 y (act) N.R.
De Potter et al. (1996) Mixed Wills Eye Hospital N.R. 93 Mean: 78.0 85% at 41 months 12% at 44 months
Quivey et al. (1993) 125I University of California, San Francisco 1983-1990 239 Mean: 35.9 82% at 5 y (act) 12% at 5 y (act)
Fontanesi et al. (1993) 125I University of Tennessee 1984-1991 144 Median: 46.0
Range: 25.0-90.0
94.4% at 5 y and at 8 y 5.6%
Packer et al. (1992) 125I North Shore University Hospital – Cornell University Medical College N.R. 64 Mean: 64.9 92.2% at 5 y 15.6% at 5 y
17.2% at 6 y

N.R. – not reported