TABLE 1.

Design of experiments for combination treatments with intralesional cidofovir and DNA vaccinations

Test group	Intralesional cidofovir	DNA vaccination(s)
Expt no. 1
Group A	None	None
Group B	None	CRPV E1 + E2 + E6 (days 83, 120, 155)
Group C	2 sites treated, from day 35 to 80	CRPV E1 + E2 + E6 (day 120)
Group D	2 sites treated, from day 35 to 80	Vector alone (day 120)
Group E	4 sites treated, from day 35 to 80	CRPV E1 + E2 + E6 (days 83, 120, 155)
Group F	4 sites treated, from day 35 to 80	Vector alone (days 83, 120, 155)
Expt no. 2
Group A	4 sites treated, from day 45 to 100	Vector alone (days 21, 35, 50, 120)
Group B	4 sites treated, from day 45 to 100	CRPV E1 + E2 (days 21, 35, 50, 120)
Group C	4 sites treated, from day 45 to 100	CRPV E6 + E7 (days 21, 35, 50, 120)
Group D	4 sites treated, from day 45 to 100	CRPV E1 + E2 + E6 + E7 (days 21, 35, 50, 120)