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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Infect Control Hosp Epidemiol. 2021 Apr 5;43(2):191–198. doi: 10.1017/ice.2021.87

Table 2 –

Rates of dental antibiotic drug class prescribed per 1000 population in 2017 by country.

Drug class Australia England United States British Columbia
Penicillins
 Amoxicillin prescription items, Number 524,166 1,959,346 14,607,292 223,057
 Rate per 1000 population (95% CI) 21.3 (21.3–21.4) 35.2 (35.2–35.3) 44.9 (44.9–44.5) 46.3 (46.1–46.5)
 Amoxicillin/Clavulanic Acid prescription items, Number 92,903 15,578 710,856 7,954
 Rate per 1000 population (95% CI) 3.8 (3.8–3.8) 0.3 (0.3–0.3) 2.2 (2.2–2.2) 1.7 (1.6–1.7)
 Phenoxymethylpenicillin prescription items, Number 11,197 12,873 2,194,226 20,999
 Rate per 1000 population (95% CI) 0.5 (0.4–0.5) 0.2 (0.2–0.2) 6.8 (6.8–6.8) 4.4 (4.3–4.4)
 Other Penicillin prescription items, Number 389 - 23,948 43
 Rate per 1000 population (95% CI) 0.0 (0.0–0.0) 0.0 (0.0–0.0) 0.1 (0.1–0.1) 0.0 (0.0–0)
Cephalosporins
 Cefalexin prescription items, Number 24,056 5,593 886,761 2,515
 Rate per 1000 population (95% CI) 1.0 (1.0–1.0) 0.1 (0.1–0.1) 2.7 (2.7–2.7) 0.5 (0.5–0.5)
 Other Cephalosporins prescription items, Number 676 627 32,794 102
 Rate per 1000 population (95% CI) 0.0 (0.0–0.0) 0.0 (0.0–0.0) 0.1 (0.1–0.1) 0.0 (0.0–0.0)
Lincosamides
 Clindamycin prescription items, Number 41,324 14,253 3,367,880 38,866
 Rate per 1000 population (95% CI) 1.7 (1.7–.1.7) 0.3 (0.3–0.3) 10.4 (10.4–10.4) 8.1 (8.0–8.1)
Macrolides
 Azithromycin prescription items, Number - 2,236 1,021,272 3,363
 Rate per 1000 population (95% CI) - 0.0 (0.0–0.0) 3.1 (3.1–3.1) 0.7 (0.7–0.7))
 Erythromycin prescription items, No. 9,598 107,047 40,268 2,096
 Rate per 1000 population (95% CI) 0.4 (0.4–0.4) 1.9 (1.9–1.9) 0.1 (0.1–0.1) 0.4 (0.4–0.5)
 Other Macrolides prescription items, Number 1,422 7,654 19,432 1,614
 Rate per 1000 population (95% CI) 0.1 (0.1–0.1) 0.1 (0.1–0.1) 0.1 (0.1–0.1) 0.3 (0.3–0.3)
Nitroimidazoles
 Metronidazole prescription items, Number 108,041 846,207 206,682 8,651
 Rate per 1000 population (95% CI) 4.4 (4.4–4.4) 15.2 (15.2–15.3) 0.6 (0.6–0.6) 1.8 (1.8–1.8)
Tetracyclines
 Doxycycline prescription items, Number 1,719 4,611 301,508 2,008
 Rate per 1000 population (95% CI) 0.1 (0.1–0.1) 0.1 (0.1–0.1) 0.9 (0.9–0.9) 0.4 (0.4–0.4)
 Tetracycline prescription items, Number - 914 3,874 199
 Rate per 1000 population (95% CI) - 0.0 (0.0–0.0) 0.0 (0.0–0.0) 0.0 (0.0–0.0)
 Other Tetracyclines prescriptions, Number - 491 11,304 48
 Rate per 1000 population (95% CI) - 0.0 (0.0–0.0) 0.0 (0.0–0.0) 0.0 (0.0–0.0)
Other
 Other antibiotic prescription items, Number 642 - 165,440 1,432
 Rate per 1000 population (95% CI) 0.0 (0.0–0.0) - 0.5 (0.5–0.5) 0.3 (0.3–0.3)