In vitro activity of compounds 5a-l against T. spiralis ML after 24 h and 48 h of exposure^a.

Comp.	Concentrations 50 (100) μg ml−1 in μM	Efficacyb (%)		Efficacyb (%)
		After 24 h		After 48 h
		50 μg ml−1	100 μg ml−1	50 μg ml−1	100 μg ml−1
5a	0.198 (0.396)	72.45	90.05	80.07	95.44
5b	0.186 (0.372)	100.00	100.00	100.00	100.00
5c	0.186 (0.372)	95.03	95.78	98.05	98.87
5d	0.186 (0.372)	100.00	100.00	100.00	100.00
5e	0.176 (0.352)	90.03	100.00	94.87	100.00
5f	0.188 (0.376)	5.74	15.34	24.60	40.25
5g	0.169 (0.337)	95.45	95.67	98.58	100.00
5h	0.169 (0.337)	10.33	95.20	28.17	97.98
5i	0.153 (0.306)	90.46	95.00	94.95	98.06
5j	0.177 (0.354)	40.15	100.00	61.47	100.00
5k	0.177 (0.354)	90.09	95.87	95.00	98.79
5l	0.177 (0.354)	85.43	100.00	91.03	100.00
Albendazole	0.188 (0.377)	10.68	10.80	14.63	15.61
Ivermectin	0.057 (0.114)	45.39	49.10	62.17	78.83

^aControl – 100 parasites.

^b p < 0.05.