Copper-based nano-catalyst catalyzed protocol for the synthesis of 5-substituted tetrazole containing scaffolds via one-pot MCR of aldehydes with hydroxylamine and azide.
Entry | Catalyst | Solvent | Catalyst loading | Temperature (°C) | Time (h) | Yield (%) | Ref. |
---|---|---|---|---|---|---|---|
1 | Fe3O4@SiO2-PVA/Cu(ii) | H2O | 0.5 mol% | 100 | 4 | 92 | 91 |