Table 3.
Long-term outcomes of the women versus men in the propensity score-matched cohorts
| Outcome/subgroup | Women | Men | HR/SHR of women (95% CI) | P for interaction |
|---|---|---|---|---|
| Primary outcome | ||||
| Cardiovascular death | 0.450 | |||
| PCI | 1868 (14.3%) | 1899 (14.5%) | 0.99 (0.93–1.05) | |
| CABG | 343 (20.0%) | 320 (18.6%) | 1.05 (0.90–1.23) | |
| Acute myocardial infarction (AMI) | 0.080 | |||
| PCI | 1044 (8.0%) | 1091 (8.4%) | 0.96 (0.88–1.04) | |
| CABG | 94 (5.5%) | 75 (4.4%) | 1.27 (0.94–1.71) | |
| Ischemic stroke | 0.157 | |||
| PCI | 774 (5.9%) | 793 (6.1%) | 0.98 (0.89–1.08) | |
| CABG | 112 (6.5%) | 137 (8.0%) | 0.81 (0.63–1.04) | |
| Primary composite outcomea | 0.582 | |||
| PCI | 3069 (23.5%) | 3168 (24.3%) | 0.97 (0.92–1.02) | |
| CABG | 457 (26.6%) | 445 (25.9%) | 1.01 (0.88–1.15) | |
| Secondary outcome | ||||
| All-cause mortality | 0.723 | |||
| PCI | 4752 (36.4%) | 4826 (37.0%) | 0.99 (0.95–1.02) | |
| CABG | 956 (55.7%) | 968 (56.4%) | 0.97 (0.89–1.06) | |
| Admission for heart failure | 0.0496 | |||
| PCI | 1360 (10.4%) | 1048 (8.0%) | 1.32 (1.22–1.43) | |
| CABG | 244 (14.2%) | 227 (13.2%) | 1.09 (0.91–1.30) | |
| Revascularization (PCI or CABG) | 0.021 | |||
| PCI | 3674 (28.1%) | 4232 (32.4%) | 0.84 (0.81–0.88) | |
| CABG | 151 (8.8%) | 138 (8.0%) | 1.11 (0.88–1.39) | |
| Safety outcome | ||||
| Major bleeding | 0.296 | |||
| PCI | 350 (2.7%) | 382 (2.9%) | 0.92 (0.79–1.06) | |
| CABG | 56 (3.3%) | 49 (2.9%) | 1.14 (0.78–1.68) | |
| GI bleeding | 0.351 | |||
| PCI | 1944 (14.9%) | 2034 (15.6%) | 0.95 (0.90–1.01) | |
| CABG | 263 (15.3%) | 255 (14.9%) | 1.04 (0.88–1.23) | |
| Intracranial hemorrhage | 0.738 | |||
| PCI | 85 (0.7%) | 104 (0.8%) | 0.82 (0.62–1.09) | |
| CABG | 13 (0.8%) | 18 (1.0%) | 0.72 (0.35–1.47) |
Data were given as frequency (percentage)
PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, HR hazard ratio, SHR subdistribution hazard ratio, CI confidence interval, GI gastrointestinal
aIncluding cardiovascular death, acute myocardial infarction and ischemic stroke