Fig. 2.

Circ_0001875 promotes the proliferation, migration and invasion of NSCLC cells in vitro. a Relative expression of circ-0001875 and FAM120A mRNA in A549 and H1299 cells after transfection with circ-0001875 siRNA and overexpression vector (si-circ-0001875 and circ-0001875) and the controls (si-NC and vector). b–d CCK8 and colony formation assays were performed to evaluate cell proliferation in the indicated cell lines. e–f Wound healing assay was used to assess the migration ability in A549 and H1299 cells transfected as indicated. g–h The migration and invasion abilities of cells transfected as indicated were detected by Transwell assays. Images are shown at 100 × magnification. Scale bar = 100 μm. Data are shown as the means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001