TABLE 6.
Susceptibilities of the B. fragilis group species to the various test antimicrobial agentsa
| Antimicrobial agent | Results (MIC90 of drugb/% susceptibility of bacteria) with:
|
|||||||
|---|---|---|---|---|---|---|---|---|
| B. fragilis group | B. fragilis | B. thetaiotaomicron | B. distasonis | B. ovatus | B. vulgatus | B. uniformis | B. caccae | |
| Piperacillin-tazobactam | 4/100 | 1/100 | 4/100 | 8/100 | 4/100 | 2/100 | 2/100 | 1/100 |
| Ampicillin-sulbactam | 16/89 | 8/92 | 8/90 | 32/67 | 16/88 | 16/88 | 16/86 | 8/96 |
| Penicillin G | >32/0 | >32/0 | >32/0 | >32/0 | >32/0 | >32/0 | 16/0 | >32/0 |
| Cefoxitin | 16/92 | 16/93 | 16/90 | 32/89 | 16/95 | 16/91 | >32/81 | 16/96 |
| Imipenem | 0.25/99.8 | 0.25/99.4 | 0.12/100 | 0.5/100 | 0.25/100 | 0.25/100 | 0.25/100 | 0.12/100 |
| Meropenem | 0.5/98.8 | 0.5/98 | 0.5/100 | 0.5/100 | 0.5/100 | 0.5/97 | 0.5/95 | 0.5/100 |
| Ciprofloxacin | 32/9.5 | 32/13 | 32/7 | 16/7 | >32/0 | >32/6 | >32/14 | >32/5 |
| Trovafloxacin | 2/93 | 2/93 | 2/99 | 2/96 | 2/93 | 16/76 | 2/91 | 2/91 |
| Clindamycin | >16/71 | >16/71 | >16/77 | >16/59 | >16/59 | >16/70 | >16/76 | >16/73 |
| Metronidazole | 1/100 | 1/100 | 1/100 | 1/100 | 1/100 | 1/100 | 1/100 | 1/100 |
a
A total of 401 B. fragilis group isolates were tested. See Table 1 for the number of isolates tested for each species.
b
MIC90s are expressed in micrograms per milliliter.