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. 2022 Apr 13;13:786767. doi: 10.3389/fphar.2022.786767

FIGURE 2.

FIGURE 2

Predicted risk change for the composite kidney (doubling of serum creatinine or ESKD) and the composite cardiovascular (non-fatal myocardial infarction, non-fatal stroke, or cardiovascular death) outcome in the total population based on single risk marker as well as the PRE score, using risk markers changes from baseline to 6-months or first available follow up (N = 9,340). Bars indicate estimates of the mean change in relative risk for specific outcomes with 95% confidence intervals, as compared to placebo. HbA1c, glycated hemoglobin; BP, blood pressure; UACR, urinary-albumin-creatinine-ratio; HDL, high-density-lipoprotein; LDL, low-density-lipoprotein; PRE score, Parameter Response Efficacy score; ESKD, end stage kidney disease.