The Lachnospiraceae are important when determining the difference between the microbiota of mice challenged with WT and ΔhypD. (A) Relative abundance at the family level for no C. diff, hypD, and WT fecal microbiome for days 0, 2, 4, and 6 postchallenge and the cecal microbiome for day 7 postchallenge. (B) Top 8 ASVs driving differences between hypD and WT cecal microbiome on day 7 postchallenge. Significant ASVs (q < 0.1) are bolded.