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Transcriptomic differences in response to hydroxyproline vary between C. difficile and commensal Clostridia. Heatmap of genes that had significantly differential expression in (A) C. difficile WT, (B) C. hiranonis, (C) C. hylemonae, and (D) C. scindens between analyses was run using Geneious and DESeq2. All genes considered differentially expressed had an adjusted P value of <0.05 and ±1 log fold change.
