. 2001 Apr;45(4):1244–1248. doi: 10.1128/AAC.45.4.1244-1248.2001

TABLE 2.

Activities of Q-D and rifampin against three strains of S. aureus with different phenotypes of resistance to MLS antibiotics after 4 days of treatment in rabbit endocarditis

Regimen	Log₁₀ CFU/g of vegetation (no. of sterile/no. of treated animals) with strain:
Regimen	HM1054 (Q^s D^s)	RP13 (Q^s D^r)	HM1054R (Q^r D^s)
Controls	10.2 ± 0.6 (—/14)^a	9.1 ± 0.6 (—/8)^a	9.1 ± 1.1 (—/7)
Q-D	4.3 ± 1.2 (1/9)^a ^b	5.6 ± 1.5 (1/12)^a ^b	7.3 ± 0.5 (0/5)
Rifampin	5.1 ± 3.4 (2/4)^b	4.0 ± 2.2 (1/6)^b	Not done
Q-D + rifampin	2.0 ± 0.3 (6/6)^c	2.2 ± 1.0 (9/10)^c	7.6 ± 1.4 (0/13)

Results previously published (23).

P < 0.01 versus controls.

P < 0.01 versus Q-D alone and rifampin alone.