TABLE 2.
Type and severity of lesions by straina
| Histological feature | Avg pathology score by strain: |
||
|---|---|---|---|
| WT | dltB_ST121 | Δrot/dltB_ST121 | |
| Serocellular crust | 1.1 | 3.2 | 2.7 |
| Granulation tissue | 2.8 | 5.0 | 4.0 |
| Loss of pilosebaceous units | 2.1 | 5.0 | 5.0 |
| Perivasculitis, lymphoplasmacytic and histiocytic | 1.6 | 1.0 | 1.0 |
| Panniculitis | 0.6 | 3.6 | 2.3 |
a
All tissue samples were examined and scored by a board-certified veterinary pathologist. A severity score for each lesion was determined based on the following criteria: 0 = not present, 1 = mild, 3 = moderate, 5 = severe.