TABLE 5.
Sensitivity analyses for association between nut consumption and risk of cognitive impairment.
Nut consumption | Total | Cases | Model 1 |
Model 2 |
Model 3 |
|||
RR (95% CI) | P value | RR (95% CI) | P value | RR (95% CI) | P value | |||
Sensitivity analysis 1: in participants attending the follow-up survey and completing MMSE at least twice | ||||||||
None or not weekly | 6383 | 2479 | 1.00 (Ref) | – | 1.00 (Ref) | – | 1.00 (Ref) | – |
<70 g/week | 311 | 90 | 0.75 (0.62–0.90) | <0.01 | 0.83 (0.69–1.00) | 0.05 | 0.85 (0.70–1.03) | 0.09 |
≥70 g/week | 1166 | 335 | 0.73 (0.66–0.81) | <0.01 | 0.81 (0.73–0.90) | <0.01 | 0.83 (0.75–0.92) | <0.01 |
P for trend | <0.01 | <0.01 | <0.01 | |||||
Sensitivity analysis 2: using MMSE score <24 to define cognitive impairment | ||||||||
None or not weekly | 5584 | 3278 | 1.00 (Ref) | – | 1.00 (Ref) | – | 1.00 (Ref) | – |
<70 g/week | 318 | 164 | 0.83 (0.74–0.94) | <0.01 | 0.89 (0.79–1.00) | 0.06 | 0.93 (0.82–1.04) | 0.20 |
≥70 g/week | 1158 | 546 | 0.79 (0.73–0.85) | <0.01 | 0.90 (0.85–0.97) | <0.01 | 0.93 (0.86–0.99) | 0.03 |
P for trend | <0.01 | <0.01 | 0.02 |
RR, relative risk; CI, confidence interval; g/week, grams per week; MMSE, mini-mental state examination. Variables in model 1, model 2, and model 3 were same as those in Table 2.
The bold values mean “P < 0.05”.