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. 2022 Apr 13;14:816443. doi: 10.3389/fnagi.2022.816443

TABLE 5.

Sensitivity analyses for association between nut consumption and risk of cognitive impairment.

Nut consumption Total Cases Model 1
Model 2
Model 3
RR (95% CI) P value RR (95% CI) P value RR (95% CI) P value
Sensitivity analysis 1: in participants attending the follow-up survey and completing MMSE at least twice
None or not weekly 6383 2479 1.00 (Ref) 1.00 (Ref) 1.00 (Ref)
<70 g/week 311 90 0.75 (0.62–0.90) <0.01 0.83 (0.69–1.00) 0.05 0.85 (0.70–1.03) 0.09
≥70 g/week 1166 335 0.73 (0.66–0.81) <0.01 0.81 (0.73–0.90) <0.01 0.83 (0.75–0.92) <0.01
P for trend <0.01 <0.01 <0.01
Sensitivity analysis 2: using MMSE score <24 to define cognitive impairment
None or not weekly 5584 3278 1.00 (Ref) 1.00 (Ref) 1.00 (Ref)
<70 g/week 318 164 0.83 (0.74–0.94) <0.01 0.89 (0.79–1.00) 0.06 0.93 (0.82–1.04) 0.20
≥70 g/week 1158 546 0.79 (0.73–0.85) <0.01 0.90 (0.85–0.97) <0.01 0.93 (0.86–0.99) 0.03
P for trend <0.01 <0.01 0.02

RR, relative risk; CI, confidence interval; g/week, grams per week; MMSE, mini-mental state examination. Variables in model 1, model 2, and model 3 were same as those in Table 2.

The bold values mean “P < 0.05”.