TABLE 2.
Characteristic features of distribution of samples among different clusters identified through unsupervised cluster analysis based upon expression data of six prioritized genes and other epidemiology details
| Features in clusters | Cluster-1 | Cluster-2 | Cluster-3 | Cluster-4 |
|---|---|---|---|---|
| Sample no., n (%) | 18 (22) | 19 (23) | 15 (18) | 28 (35) |
| IGRA | Negative | Negative | Positive | Positive |
| Expression level of FCGR1B (avg ΔCt) | 5.95 (Lowest exp) | 4.12 | 2.90 (Highest exp) | 4.93 |
| Expression level of GBP1 (avg ΔCt) | 8.71 (Lowest exp) | 3.39 | 1.66 (Highest exp) | 5.77 |
| Expression level of GBP5 (avg ΔCt) | 10.49 (Lowest exp) | 3.95 | 2.29 (Highest exp) | 8.23 |
| Female:Male | 7:11 (0.63) | 10:9 (1.11) | 10:5 (2.0) | 11:17 (0.64) |
| TB2-TB1 | –0.17 to 0.1 | –0.17 to 0.51 | –7.25 to 7.44 | –4.65 to 2.48 |
| Age (range) | 15-63 | 15-50 | 16-53 | 14-58 |
| Age (mode) | 15 | 25 | 35 | 40 |
| Age (avg) | 33.44 | 32.6 | 31.4 | 32.14 |
| Age (median) | 32.5 | 27 | 33 | 29.5 |