Neutralization and ADE activities found in serum samples against pseudotyped virus. Fifty representative serum samples from COVID-19 convalescents (numbers 26–46), acute patients with mild (numbers 48, 51, 56, 57, 60, 62, 67, and 70), moderate (numbers 74, 76, 80–82, 84–87, 91, 92, 94, and 95), and severe (numbers 96–98, 101, 105, 108, 111, and 114) symptoms were investigated. The relative numbers of infected cells were calculated by setting the number of GFP-positive cells in the absence of the serum to 100%. Each experiment was done twice and results are shown as means and standard deviations. ADE-positive sample numbers are shown in red.