TABLE 2.

Univariate and multivariate logistic regression analysis for KPC-Kp infection among colonized patients^a

Variables	Univariate analysis		Multivariate analysis
	OR (95% CI)	P value	OR (95% CI)	P value
Age, per unit	0.98 (0.96–1.00)	0.05
Female gender	1.57 (0.83–2.98)	0.17
Prior admission to intensive care unit (previous 6 mo)	1.77 (0.96–3.29)	0.07
High-risk ward	3.10 (1.63–5.89)	<0.001	4.77 (1.61–14.10)	0.005
High-risk period (July 2012–June 2014)	2.04 (1.10–3.80)	0.02	2.30 (0.98–5.46)	0.06
Institutionalized	0.72 (0.28–1.87)	0.51
Urological manipulation during follow-up	4.02 (1.63–9.94)	0.002	3.69 (1.08–12.60)	0.04
Central venous catheterization during follow-up	3.62 (1.90–6.92)	<0.001
Mechanical ventilation during follow-up	3.00 (1.56–5.78)	0.001
Major surgery during follow-up	1.34 (0.64–2.82)	0.43
Major surgery in the previous 3 mo	1.54 (0.83–2.83)	0.17
Nasogastric intubation during follow-up	1.25 (0.59–2.64)	0.55
Diabetes mellitus	0.63 (0.33–1.21)	0.17
Heart failure	0.71 (0.37–1.39)	0.32
Chronic obstructive pulmonary disease	1.11 (0.55–2.21)	0.78
Kidney disease	1.00 (0.47–2.14)	0.99
Neoplasia	1.06 (0.54–2.06)	0.86
Neutropenia	2.19 (0.86–5.54)	0.10
Charlson index, per unit	0.93 (0.81–1.06)	0.27
Arterial hypertension	0.73 (0.39–1.36)	0.32
Solid organ transplantation	1.00 (0.37–2.74)	0.99
Dialysis	2.73 (0.90–8.23)	0.07
Chemotherapy/radiation in previous 3 mo	1.64 (0.50–5.38)	0.42
Gianella risk score (GRS), per unit	1.48 (1.31–1.68)	<0.001	1.51 (1.32–1.73)	<0.001
Colonization during follow-up	2.75 (1.37–5.53)	0.004	2.74 (1.07–7.04)	0.03

^aCPE, carbapenemase-producing Enterobacterales; KPC-Kp, Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae; SHRs: subdistribution hazard ratios.