TABLE 4.
The quantity of polA and Tpp47 in urine and plasma in patients with different stages of syphilisa
| Stages | Urine supernatant (copies/mL) |
Urine sediment (copies/mL) |
Plasma (copies/mL) |
|||
|---|---|---|---|---|---|---|
| polA | Tpp47 | polA | Tpp47 | polA | Tpp47 | |
| Primary | 59.4 (16.5 to 1,551) | 50.6 (9.9 to 1,562) | 148.5 (10.45 to 1,216) | 59.4 (5.5 to 1,331) | 23.1 (17.6 to 50.05) | 27.5 (0 to 62.15) |
| Secondary | 17.6 (0 to 20.35) | 44 (11.55 to 66.55) | 209 (22 to 649)b,c | 253 (29.15 to 1,029)c | 19.8 (0 to 37.4) | 19.8 (0 to 43.45) |
| Latent | 88 (0 to 176) | 291.5 (55 to 528) | 0 (0 to 198) | 220 (0 to 220) | 0 (0 to 0) | 20.9 (0 to 41.8) |
| Symptomatic neurosyphilis | 0 | 55 | 0 | 0 | 0 (0 to 0) | 0 (0 to 0) |
| All cases | 18.7 (0 to 80.85) | 49.5 (18.7 to 153.5) | 148.5 (4.95 to 649)b,c | 101.2 (19.8 to 1,029)c | 19.8 (0 to 37.95) | 19.8 (0 to 44)b |
aThe loads of polA and Tpp47 in urine supernatant from all cases (n = 30), primary syphilis (n = 9), secondary syphilis (n = 18), latent syphilis (n = 2), and symptomatic neurosyphilis (n = 1) are shown. The loads of polA and Tpp47 in urine sediment from all cases (n = 48), primary syphilis (n = 16), secondary syphilis (n = 28), latent syphilis (n = 3), and symptomatic neurosyphilis (n = 1) are also shown. Finally, the loads of polA and Tpp47 in plasma from all cases (n = 54), primary syphilis (n = 14), secondary syphilis (n = 36), latent syphilis (n = 2), and symptomatic neurosyphilis (n = 2) are shown.
bP < 0.05 compared to urine supernatant.
cP < 0.05 compared to plasma.