FIG 2.

Antibiotic treatment and C. difficile infection induced gut-dysbiosis in mice. (A) Alpha diversity plot of different treatment groups: antibiotic treatment and C. difficile infection reduced the alpha diversity of the gut microbiome as indicated by a lower Shannon index than control. (n = 4). (B) Principal coordinate analysis (PCoA) plot for beta diversity (weighted Bray-Curtis distances): both Abx and C. diff groups clustered away from control mice in terms of gut microbiota beta diversity (n = 4). (C) The relative abundance of bacteria at class level: antibiotic treatment and C. difficile infection altered the abundance of different major bacterial communities in mice (n = 4).