TABLE 1.
Characteristics of the study population
| Characteristic | Never positive | Positive for MTS or saliva | All participants |
|---|---|---|---|
| No. of participants | 44 | 14 | 58 |
| No. of sample pairs | 159 | 41 | 200 |
| No. of days of sample collection per participant, median (range) | 4 (1, 7) | 3 (1, 6) | 3 (1, 7) |
| Female, N (%) | 20 (46) | 8 (57) | 28 (48) |
| Age, mean ± SD | 26.5 ± 15.5 | 27.3 ± 13.8 | 26.7 ± 15 |
| Age group, N (%) | |||
| <18 | 2 (4) | 1 (7) | 3 (5) |
| 18-45 | 38 (86) | 11 (79) | 49 (84) |
| >45 | 4 (9) | 2 (14) | 6 (10) |
| White, N (%) | 30 (68) | 11 (79) | 41 (71) |
| BMI, mean ± SD | 25.6 ± 4.9 | 25.2 ± 4.4 | 25.5 ± 4.7 |
| Chronic respiratory illnessa, N (%) | 17 (39) | 5 (36) | 22 (38) |
| Ever smoker, N (%) | 1 (2) | 1 (7) | 2 (3) |
| Vaccination statusb, N (%) | |||
| No vaccination | 39 (89) | 14 (100) | 53 (91) |
| ≥14 days after 1st shot | 3 (7) | 0 (0) | 3 (5) |
| ≥14 days after second shot | 2 (4) | 0 (0) | 2 (3) |
| Ever symptomaticc, N (%) | 1 (2) | 13 (93) | 14 (24) |
| Symptomatic participants | |||
| Days since symptom onset at enrollment, median (range) | 2 (NAe) | 3 (−3, 14) | 2.5 (−3, 14) |
| Overall days since symptom onset of sample collection, median (range) | 6.5 (2, 12) | 5 (−3, 24) | 5 (−3, 24) |
| Loss of taste/smell, N (%) | 0 | 2 (15) | 2 (14) |
| Median upper respiratory symptomsd (IQR) | 3 (1.2, 6.2) | 2 (0, 3) | 2 (0.2, 3) |
| Median lower respiratory symptoms (IQR) | 0 (0, 0) | 0 (0, 1) | 0 (0, 1) |
| Median systemic symptoms (IQR) | 0.5 (0, 1.8) | 0 (0, 1.2) | 0 (0, 1.8) |
| Median gastrointestinal symptoms (IQR) | 0 (0, 0) | 0 (0, 0) | 0 (0, 0) |
| Temperature, mean celsius ± SD | 37 ± 0.3 | 37.2 ± 0.5 | 37.2 ± 0.4 |
Chronic respiratory illness = volunteers with any chronic obstructive pulmonary disease, asthma, or other lung diseases.
Vaccination status was summarized at the time of participants’ first sample collection. No vaccination includes 2 persons <14 days after 1st shot.
Group comparison, P < 0.05.
Symptoms at the time of each sample collection visit. Sixteen individual symptoms were rated from 0 to 3. Systemic (max score of 12) = malaise + headache + muscle/joint ache + sweats/fever/chills; gastrointestinal (max score of 12) = loss of appetite + nausea + vomit + diarrhea; lower respiratory (max score of 9) = chest tightness + shortness of breath + cough; upper respiratory (max score of 15) = runny nose + stuffy nose + sneeze + earache + sore throat.
NA, not applicable.