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. 2022 Mar 21;10(2):e00128-22. doi: 10.1128/spectrum.00128-22

TABLE 3.

Sensitivity of saliva and MTS and relative odds of detection and ratio of viral RNA copy numbers of SARS-CoV-2 in saliva by day since symptom onset among 13 mildly symptomatic contacts of known cases

Days since symptom onseta Saliva positive/N
(Sensitivity %)
MTS positive/N
(Sensitivity %)
Odds ratiob saliva: MTS Estimatesc saliva: MTS
All samplesd 31/40 (78) 28/40 (70) 1.5 (0.54, 4) 0.083 (0.069, 0.099) 
−3 through 2 10/11 (91) 5/11 (45) 12 (1.2, 130) 3.2 (2.8, 3.8) 
3 through 8 16/18 (89) 17/18 (94) 0.47 (0.037, 6) 0.03 (0.026, 0.036) 
9 through 24 5/11 (45) 6/11 (55) 0.7 (0.13, 3.8) 0.065 (0.057, 0.073) 
a

Days since symptom onset inclusive of the start and end day.

b

Odds ratios and their 95% confidence intervals were estimated using logistic regression.

c

Effect estimates and their 95% confidence intervals are shown as the ratio of RNA copy numbers of saliva to MTS. Analyses were controlled for random effects of subjects and sample nested within the subjects and for censoring by the limit of detection using a linear mixed-effects model for censored responses (R Project lmec package).

d

All samples from the 13 mildly symptomatic contacts of known cases with days since symptom onset from day −3 through day 24.