Table 1. Rate reduction of hospitalizations among SARS-CoV-2–positive persons who received the BNT162b2 COVID-19 vaccine booster dose, Israel*.

Age group, y	Time of first positive SARS-CoV-2 PCR test after index date, wk	Unvaccinated SARS-CoV-2–positive persons			Vaccinated SARS-CoV-2–positive persons		Adjusted 1 – IRR, % (95% CI)†
		Hospitalized	Total		Hospitalized	Total
16–59	2	889	22,545		4	1,343	92.2 (77.9–97.3)
	3	770	18,232		3	455	83.9 (46.7–95.1)
	4	590	12,962		2	293	84.6 (47.1–95.5)
	5	414	8,555		1	210	90.1 (44.5–98.2)
	6	259	5,531		1	138	84.3 (15.1–97.1)
	7	175	3,573		0	131	100.0
	8	120	2,626		1	83	74.0 (−52.5 to 95.6)
	9	92	2,013		0	54	100.0
	10	72	1,714		0	57	100.0
	11	69	1,401		0	66	100.0
	12	68	1,385		0	90	100.0
	13	72	1,442		0	118	100.0
	14	62	1,569		1	154	84.4 (5.9–97.4)
	15	64	2,145		4	351	62.8 (−0.6 to 86.2)
	16	71	4,088		1	884	94.0 (47.9–99.3)
	2–16 combined	1,662	41,135		18	4,427	89.2 (79.1–94.4)
>60	2	644	1,985		98	1,314	77.5 (71.5–82.3)
	3	666	2,200		39	464	73.0 (64.4–79.5)
	4	647	2,160		36	375	68.2 (52.7–78.6)
	5	619	2,164		25	319	73.2 (48.2–86.2)
	6	593	2,033		20	296	77.3 (62.5–86.3)
	7	501	1,724		29	271	64.5 (50.2–74.7)
	8	375	1,276		23	221	65.3 (40.2–79.9)
	9	254	869		6	147	86.7 (72.6–93.6)
	10	163	577		10	86	64.1 (27.1–82.3)
	11	108	376		9	63	54.9 (−35.9 to 85.1)
	12	80	258		4	44	71.0 (21.5–89.3)
	13	56	208		3	52	80.2 (54.4–91.4)
	14	56	183		3	49	81.9 (45.8–94.0)
	15	58	170		6	47	67.5 (32.6–84.4)
	16	53	162		5	44	65.7 (23.4–84.6)
	17	46	151		1	56	94.4 (57.3–99.2)
	18	42	147		1	69	95.0 (72.1–99.1)
	19	38	184		5	125	82.6 (57.7–92.8)
	20	46	305		13	432	81.4 (67.0–89.5)
	2–20 combined	1,976	6,673		336	4,474	75.1 (71.3–78.5)

*COVID-19, coronavirus disease; IRR, incidence rate ratio; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2. †Adjusted for sex and epidemiologic week.