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. 2022 May;28(5):977–985. doi: 10.3201/eid2805.211965

Table 4. Estimations of overall population-level immunity against historical H2 and H1 pandemic viruses and the potential effect of population immunity on reproduction number among persons in Hong Kong, China*.

Virus strain Proportion of population immune (95% CI) Relative reduction in R0 (95% CI) Smallest R0 needed to cause pandemic (95% CI)
A/Singapore/1/1957 (H2N2)
0.37 (0.346–0.394)
0.321 (0.295–0.348)
1.472 (1.419–1.535)
A/California/04/2009 (H1N1) 0.117 (0.098–0.14) 0.115 (0.096–0.138) 1.13 (1.106–1.16)

*Serum samples for testing antibodies to the 1957 virus were collected in 2011 and those for testing antibodies to the 2009 virus were collected in 2008–2009.