Suppressed endogenous PTH concentrations and sex-specific impact on calcium, alkaline phosphatase, and IGF-1 concentrations in continuously PTH-infused 0CNIgf1r−/− mice. Serum intact PTH (A), total calcium (B), alkaline phosphatase (C), and IGF-1 (D) concentrations in continuously PTH- and vehicle-infused 0CNIgf1r−/− and control mice (n=8–12). The error bars enclose mean ± SE; *p < 0.05.