. Author manuscript; available in PMC: 2022 Apr 27.

Published in final edited form as: Mol Nutr Food Res. 2019 Dec 11;64(15):e1900995. doi: 10.1002/mnfr.201900995

Table 3.

Effects of different RR polyphenol fractions on blood chemistry and lipid profile.

	L	H	H+W	H+S	H+P

Triglyceride (mmol/L)	0.64 ± 0.10^b	1.14 ± 0.10^a	1.02 ± 0.04 ^a	0.89 ± 0.09 ^ab	0.77 ± 0.06 ^b
Total cholesterol (mg/dL)	172.0 ± 37.8 ^b	298.2 ± 16.0^a	236.9± 20.8^b	312.9 ± 9.1 ^a	217.3 ± 34.6 ^b
HDL-C (mg/dL)	81.4 ± 18.5^c	141.4 ± 7.1 ^b	153.9 ± 15.0^ab	183.1 ± 9.1^a	161.4 ± 13.2^ab
LDL, VLDL-C (mg/dL)	24.1 ± 5.4^b	43.7 ± 5.2^a	27.3 ± 3.8^b	35.9 ± 2.3^ab	31.8 ± 4.4^ab
NEFA (mmol/L)	0.41 ± 0.03^b	0.51 ± 0.03^a	0.50 ± 0.03^ab	0.44 ± 0.02^b	0.49 ± 0.03^ab
Glycerol (mmol/L)	0.20 ± 0.03^b	0.27 ± 0.04^a	0.28 ± 0.02^a	0.27 ± 0.04^a	0.22 ± 0.04^b
Adiponectin (μg/mL)	11.2 ± 0.9^a	8.10 ± 0.5^b	8.8 ± 0.4^b	8.7 ± 1.1^b	12.5 ± 1.0^a
Fasting Glucose (mg/dL)	70.5 ± 3.4^b	125.0 ± 11.4^a	84.0 ± 10.0^b	123.5 ± 4.9^a	86.3 ± 7.7^b
Fasting Insulin (ng/mL)	0.07 ± 0.02^c	0.60 ± 0.21^a	0.46 ± 0.13^a	0.88 ± 0.17^a	0.22 ± 0.02^b

Values represent the mean ± SEM (n=8 per group), Columns not sharing a common letter are significantly different (p< 0.05) by one-way ANOVA with Tukey’s post hoc multiple analysis. L: low fat; H: high fat; H+W: high fat with polyphenols from whole fruits (0.4% w/w); H+S: high fat diet with RR polyphenols from seed fraction (0.1% w/w); H+P: high fat with RR polyphenols from pulp fraction (0.3% w/w); NEFA, non-esterified free fatty acids.