Time-kill curves for A. hydrophila A136 with cefotaxime (CTX) and minocycline (MIN). (a) ⧫, control; ■, CTX at 0.75 μg/ml; ▴, MIN at 2 μg/ml; ×, MIN at 3 μg/ml; ○, CTX at 0.75 μg/ml plus MIN at 2 μg/ml; ▵, CTX at 0.75 μg/ml plus MIN at 3 μg/ml. (b) ▵, control; ■, CTX at 3 μg/ml; ⧫, MIN at 3 μg/ml; ○, CTX at 3 μg/ml plus MIN at 3 μg/ml.