Table 4. Association of antimicrobial use and carbapenemase production (N = 132).
| Variable | CP | CN | COR (95%CI) P-value | AOR (95%CI) P-value* | |
|---|---|---|---|---|---|
| Antimicrobial therapy | Yes | 27 | 89 | 4.55 (0.57–36.05) 0.151 | 1.82 (0.19–17.91) 0.607 |
| No | 1 | 15 | 1 | 1 | |
| Carbapenems | Yes | 11 | 9 | 6.83 (2.46–18.96) <0.001 | 6.03 (2.13–17.09) 0.004 |
| No | 17 | 95 | 1 | 1 | |
| 3rd or 4th GCs | Yes | 21 | 62 | 2.03 (0.79–5.21) 0.140 | 1.67 (0.56–5.04) 0.478 |
| No | 7 | 42 | 1 | 1 | |
| Quinolones | Yes | 4 | 10 | 1.57 (0.45–5.43) 0.479 | _ |
| No | 24 | 94 | 1 | ||
| Aminoglycosides | Yes | 12 | 31 | 1.77 (0.75–4.17) 0.194 | 1.70 (0.66–4.38) 0.538 |
| No | 16 | 73 | 1 | 1 | |
CP: Carbapenemase positive, CN: Carbapenemase negative, 3rd or 4th GCs: Third or fourth-generation cephalosporins, COR: Crude odds ratio, AOR: Adjusted odds ratio, CI: Confidence interval
* FDR adjusted P-value.