Fig 5. Depletion of SufT results in deregulation of metabolites dependent on Fe-S cluster proteins.

Single column based LC MS/MS analysis of (A) OBHA derivatized TCA metabolites, underivatized measurement of purines, SAM, Cystathione (CTH), SAH and (B) Amino acids of SufT-KD strain post 72 h of ATc (200 ng/mL) treatment. Experiments were performed in biological triplicate and p value was calculated by two-way ANOVA multiple comparison test. ns p ≥ 0.05, *p ≤0.05, **p ≤0.01, ***p ≤0.001.