Fig. 6. Chronic pain enhances the excitability of ovBNST^CART neurons.

(A) Representative action potentials in ovBNST^CART neurons of sham (black) and nerve-injured (blue) mice. (B to E) Intrinsic electrophysiological properties of ovBNST^CART neurons of sham (black, n = 20 cells from four mice) and nerve injury (blue, n = 22 cells from four mice) mice: resting membrane potential (B), relationship between action potential threshold and rheobase (C), membrane resistance (D), and action potential amplitude (E). Data are expressed as means ± SEM. Statistical significance was evaluated using two-tailed unpaired t test. *P < 0.05 and **P < 0.01. Details of statistical data are provided in table S1.