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. 2022 Apr 26;37(1):1120–1195. doi: 10.1080/14756366.2022.2061966

Table 4.

Structure and activity of phenolic acids against hyaluronidase.

Structure Name IC50(μM) References
Inline graphic
Rosmarinic acid
545
Iwanaga et al.46
Inline graphic
Isoferulic acid
>2000
Iwanaga et al.46
Inline graphic
Ferulic acid
>2000
Iwanaga et al.46
Inline graphic
Caffeic acid
>2000
Iwanaga et al.46
graphic file with name IENZ_A_2061966_ILG0021_B.jpg Cimicifugic acid K 255 Iwanaga et al.46
Inline graphic
Cimicifugic acid L
102
Iwanaga et al.46
Inline graphic
Cimicifugic acid M
173
Iwanaga et al.46
Inline graphic
Cimicifugic acid N
120
Iwanaga et al.46
Inline graphic
Shomaside A
573
Iwanaga et al.47
graphic file with name IENZ_A_2061966_ILG0026_B.jpg Shomaside B 430 Iwanaga et al.47
Inline graphic
Shomaside C
663
Iwanaga et al.47
Inline graphic
Shomaside D
>658
Iwanaga et al.47
Inline graphic
Cimicifugic acid H
525
Iwanaga et al.47
Inline graphic
Cimicifugic acid I
143
Iwanaga et al.47
graphic file with name IENZ_A_2061966_ILG0031_B.jpg Cimicifugic acid J 193 Iwanaga et al.47
Inline graphic
Fukinolic acid
144
Iwanaga et al.47
Inline graphic
Cimicifugic acid A
112
Iwanaga et al.47
Inline graphic
Cimicifugic acid B
82
Iwanaga et al.47
Inline graphic
Cimicifugic acid C
251
Iwanaga et al.47
Inline graphic
Cimicifugic acid D
153
Iwanaga et al.47
graphic file with name IENZ_A_2061966_ILG0037_B.jpg Cimicifugic acid E 120 Iwanaga et al.47
Inline graphic
Cimicifugic acid F
92
Iwanaga et al.47
Inline graphic
Cimicifugic acid G
138
Iwanaga et al.47
graphic file with name IENZ_A_2061966_ILG0040_B.jpg Clinopodic J 206 Aoshima et al.40
Inline graphic
Clinopodic K
63
Aoshima et al.40
graphic file with name IENZ_A_2061966_ILG0042_B.jpg Clinopodic L 26 Aoshima et al.40
Inline graphic
Clinopodic M
19
Aoshima et al.40
graphic file with name IENZ_A_2061966_ILG0044_B.jpg Clinopodic N 161 Aoshima et al.40
Inline graphic
Clinopodic O
66
Aoshima et al.40
Inline graphic
Clinopodic P
25
Aoshima et al.40
graphic file with name IENZ_A_2061966_ILG0047_B.jpg Rosmarinic acid   Aoshima et al.40
Inline graphic
Clinopodic acid I
112
Aoshima et al.40
graphic file with name IENZ_A_2061966_ILG0049_B.jpg Clinopodic acid E 40 Aoshima et al.40
Inline graphic
8-Epiblechnic acid
653
Aoshima et al.40
graphic file with name IENZ_A_2061966_ILG0051_B.jpg Lithospermic acid 36 Aoshima et al.40
Inline graphic
Salvianolic acid B
107
Aoshima et al.40
graphic file with name IENZ_A_2061966_ILG0053_B.jpg Salvianolic acid A 206 Aoshima et al.40
graphic file with name IENZ_A_2061966_ILG0054_B.jpg Cosmosiin >1000 Aoshima et al.40