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. 2022 Apr 6;11:e76562. doi: 10.7554/eLife.76562

Figure 4. Changes in correlated nucleotide positions in dbp3ᐃ, prp43-cs, or pxr1ᐃ mutants.

Graphical representation of modification correlation changes, significance, and location within the functional centers of the ribosome. Pairs of correlated nucleotide changes (nodes) are shown for each mutant (colored edges) relative to wild type yeast 25 S rRNA (A) and 18 S rRNA (B). In cases where correlated pairs show differential changes in correlation in different mutants (eg. U24 modifications), node color rings are fragmented with the appropriate mutant edge connecting to either the magenta (negative change in correlation relative to wild type) or black (positive change in correlation relative to wild type) portion of the node.

Figure 4.

Figure 4—figure supplement 1. Correlation analysis of dbp3ᐃ, prp43-cs, and pxr1ᐃ.

Figure 4—figure supplement 1.

Change in Spearman correlations of 18 S (A–C) and 25 S (D–E) reads in dbp3ᐃ (A/D), prp43-cs (B/E), and pxr1ᐃ (C/F) when compared to wild type. Stars represent significant changes when compared to wild type correlation and significantly different from zero correlation.