Figure 1.

Rhesus macaques treated with either saline (blue, circles) or deprenyl (2 mg/kg, red, squares) were inoculated with SIVmac251

Both SIV + saline and SIV + deprenyl group contained four animals. At 7- and 14-day post-inoculation (dpi), plasma (A) and CSF (B) from all infected macaques were assayed for viral load (copies of SIV RNA/mL) using qRT-PCR. Tissue from frontal cortex, hippocampus, caudate, corpus callosum, and spleen isolated at 14 dpi was analyzed for copies of SIV RNA per μg of RNA using RT-ddPCR (C).