Table 1.
Demographics and clinical variables for brain tumor (BT) survivors and control group
| BT survivors | Control group | |||||
|---|---|---|---|---|---|---|
| n (%) or mean (SD) | Total (n = 60) | Women (n = 21) | Men (n = 39) | Total (n = 146) | Women (n = 95) | Men (n = 51) |
| Age | 28.1 (6.8) | 30.2 (7.6) | 27.0 (6.0) | 25.0 (5.1) | 24.6 (5.4) | 25.8 (4.4) |
| Civil status | ||||||
| Married | 8 (13.3) | 6 (28.6) | 2 (5.1) | 32 (22.1) | 20 (21.3) | 12 (23.5) |
| Cohabiting partnership | 8 (13.3) | 4 (19.0) | 4 (10.3) | 51 (35.2) | 36 (38.3) | 15 (29.4) |
| Not married/cohabiting partnership | 44 (73.3) | 11 (52.4) | 33 (84.6) | 62 (42.8) | 38 (40.4) | 24 (47.1) |
| Employment | ||||||
| Working | 23 (38.3) | 11 (52.4) | 12 (30.8) | 84 (59.6) | 47 (52.2) | 37 (72.5) |
| Studying | 16 (26.7) | 4 (19.0) | 12 (30.8) | 34 (24.1) | 24 (26.7) | 10 (19.6) |
| Unemployed | 10 (16.7) | 4 (19.0) | 6 (15.4) | 10 (7.1) | 6 (6.7) | 4 (7.8) |
| Retired | 11 (18.3) | 2 (9.5) | 9 (23.1) | 0 | 0 | 0 |
| Other | 0 | 0 | 0 | 13 (9.2) | 13 (14.4) | 0 |
| BDI-IIa | 6.8 (7.2) | 9.4 (9.8) | 5.5 (5.3) | 5.7 (9.0) | 7.1 (10.0) | 2.9 (6.1) |
| Clinical cutoff for depressionb | 3 (5.2) | 2 (10.0) | 1 (2.6) | 13 (8.0) | 10 (10.5) | 3 (5.9) |
| BT survivors variables | ||||||
| Age at diagnosis | 8.5 (4.3) | 9.0 (4.6) | 8.2 (4.2) | |||
| Follow-up time in years | 19.1 (5.9, range 5–33) | 20.5 (6.1, range 9–33) | 18.3 (5.7, range 5–30) | |||
| Tumor type | ||||||
| Glial cell tumor | 27 (45.0) | 13 (61.9) | 14 (35.9) | |||
| Embryonal cell tumor | 20 (33.3) | 6 (28.6) | 14 (35.9) | |||
| Other | 12 (20.0) | 2 (9.5) | 10 (25.6) | |||
| Unknown | 1 (1.7) | 0 | 1 (2.6) | |||
| Irradiation | ||||||
| Cranial or cranio-spinal | 28 (46.7) | 7 (33.3) | 21 (53.8) | |||
| Local | 32 (53.3) | 14 (66.7) | 19 (46.2) | |||
| Ventriculo-peritoneal shunt | ||||||
| Yes | 35 (58.3) | 11 (52.4) | 24 (61.5) | |||
| No | 25 (41.7) | 10 (47.6) | 15 (38.5) | |||
| Chemotherapy | ||||||
| Yes | 38 (63.3) | 13 (61.9) | 25 (64.1) | |||
| No | 22 (36.7) | 8 (38.1) | 14 (35.9) | |||
| CTCAEc | ||||||
| 1 | 23 (38.3) | 5 (23.8) | 18 (46.2) | |||
| 2 | 22 (36.7) | 7 (33.3) | 15 (38.5) | |||
| 3 | 15 (25.0) | 9 (42.9) | 6 (15.4) | |||
| PIQ | 88.4 (13.8) | 89.7 (13.9) | 87.7 (13.9) | |||
aNorm data on BDI-II in the age group, mean (SD), women = 9.81 (8.67), men = 8.22 (8.06) [30]
bCutoff value of 20 or higher indicative of at least moderate level of depressive symptoms
cNo scores of 4 or 5 were recorded
BDI-II, Beck Depression Inventory-II; CTCAE, Common Terminology Criteria for Adverse Events; PIQ, Performance Intelligence Quotient