Table 3.

Z-factor values, divided in differentiated (multiple Z-factors) and non-differentiated (single Z-factor) according to the day of read-out (D12 → D39).

Construct	Single Z-factor	Multiple Z-factors
	D12→D39	D12	D15	D18	D20	D23	D39
3CLpro-On	0,53	0,86	0,86	0,51	0,68	0,79	0,76
3CLpro-On N-term	0,64	0,86	0,68	0,52	0,92	0,84	0,67
3CLpro-On C-term	0,11	0,29	0,75	0,72	0,56	0,34	0,66
3CLpro-On N,C-term	Read-out is always positive, with or without the inhibitor (see Supplementary Fig. 1h)