Table 1.
Demographics of patient cohorts
| GENERAL | All | CARa |
ABCD2 |
||||
|---|---|---|---|---|---|---|---|
| Low-risk | High-risk | p-value | Low-risk | High-risk | p-value | ||
| Number of patients | 101 | 29 | 29 | nab | 15 | 15 | na |
| Age – years | 72.29 (±0.83) | 71.03 (±1.51) | 73.38 (±1.63) | nsc | 70.00 (±2.54) | 73.67 (±2.46) | ns |
| Sex, women/men | 33/68 (33/67) | 10/19 (35/65) | 5/24 (17/83) | ns | 7/8 (47/53) | 6/9 (40/60) | ns |
| Smoking, present | 24 (24) | 6 (21) | 6 (21) | ns | 7 (47) | 3 (20) | ns |
| Smoking, former | 28 (28) | 9 (31) | 7 (24) | ns | 4 (27) | 3 (20) | ns |
| Smoking, never | 49 (49) | 14 (48) | 17 (59) | ns | 4 (27) | 9 (60) | ns |
| BMId | 26.2 (±0.43) | 26.6 (±0.90) | 26.3 (±0.78) | ns | 28.1 (±1.07) | 26.7 (±1.69) | ns |
| Hypertension | 96(95) | 29 (100) | 28 (97) | ns | 15 (100) | 15 (100) | na |
| Myocardial Infarction | 24 (24) | 4 (14) | 14 (48) | 0.0045 | 6 (40) | 5 (33) | ns |
| Diabetes Mellitus | 27 (27) | 5 (17) | 14 (48) | 0.0118 | 4 (27) | 5 (33) | ns |
| PVDe | 14 (13) | 3 (10) | 5 (17) | ns | 3 (20) | 3 (20) | ns |
| Antihypertensives | 83 (82) | 26 (90) | 26 (90) | ns | 14 (93) | 13 (86.7) | ns |
| Antidiabetics | 23 (23) | 4 (14) | 12 (41) | 0.0188 | 3 (20) | 5 (33) | ns |
| Lipid lowering drugs | 87 (86) | 27 (93) | 25 (86) | ns | 13 (87) | 13 (87) | ns |
| Amaurosis fugax | 23 (23) | 13 (45) | 0 | <0.0001 | 11 (73) | 0 | <0.0001 |
| TIAf | 37 (37) | 9 (31) | 11 (38) | ns | 4 (27) | 15 (100) | <0.0001 |
| Minor stroke | 11 (11) | 4 (14) | 5 (17) | ns | 0 | 0 | na |
| Major stroke | 30 (30) | 3 (10) | 13 (45) | 0.0033 | 0 | 0 | na |
Descriptive clinical data for all patients included in this study, as well as for the low and high-risk CAR and ABCD2 groups with available plaque microarrays.
Data are presented as n (%) or mean (±SEM).
a
CAR = Carotid Artery Risk score.
b
na = not applicable.
c
ns = non-significant.
d
BMI = Body Mass Index.
e
PVD = Peripheral Vascular Disease.
f
TIA = Transient Ischemic Attack.