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. 2022 Apr 8;25(5):104225. doi: 10.1016/j.isci.2022.104225

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© 2022 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Composition of the human endothelial and mesenchymal BM microenvironment

(A) Experimental design for the human BMM characterization.

(B) Scheme of customized bioinformatics pipeline filtering the cells with a large number of Immunoglobulin genes.

(C) UMAP visualization of color-coded clustering of the human BM microenvironment after filtering cells.

(D and E) Expression of representative markers for endothelial population (D) and mesenchymal-osteolineage cells (E) using an UMAP representation. See also Figure S5 and Tables S8 and S9.