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. 2022 Feb 12;13(6):1717–1740. doi: 10.1016/j.jcmgh.2022.02.005

Figure 9.

Figure 9

Expression of CD-associated risk genes across clusters. (A) Dot plots showing expression and percentage of cells expressing CD-associated risk genes (columns) across clusters (rows). For each gene, the dot color corresponds to the average scaled expression and the size of the dot corresponds to the percentage of cells in the cluster expressing the gene. (B) Uniform Manifold Approximation and Projection (UMAP) of all epithelial clusters showing MUC2 (blue) and ITLN1 (red) expression. (C) UMAP of SPIB+ cell subclusters overlain with gene expression from NOTCH2 or ATG16L2. avg.exp.scaled, average expression, scaled; pct.exp, percent of cells expressing gene.