Table 2.
Bivariate and multivariate# associations between demographic and disease factors and quality of life (EQ-5D-5L) and Social Difficulties Index inventory
| Characteristic | EQ-5D-5L index^ | Social Difficulties Index^^ | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean | Coef | SE | Beta | Multi-variate p value | Mean | Coef | SE | Beta | Multi-variate p value | |
| Total | 0.84 | 3.82 | ||||||||
| Tumour group (p value) | ||||||||||
| Breast | 0.81 | Ref | 4.97 | Ref | ||||||
| Colorectal | 0.83 | 0.02 | 0.02 | 0.04 | 0.196 | 4.54 | − 0.44 | 0.46 | − 0.03 | 0.343 |
| Melanoma | 0.89 | 0.04 | 0.02 | 0.09 | 0.006 | 2.28 | − 1.96 | 0.46 | − 0.14 | < 0.001 |
| Non-Hodgkin lymphoma | 0.82 | 0.01 | 0.02 | 0.01 | 0.697 | 4.67 | − 0.74 | 0.56 | − 0.04 | 0.189 |
| Prostate | 0.88 | 0.06 | 0.02 | 0.13 | 0.002 | 3.19 | − 1.51 | 0.56 | − 0.11 | 0.007 |
| Bivariate p value | < 0.01 | < 0.001 | ||||||||
| Years post diagnosis | ||||||||||
| 1 year | 0.83 | (Ref) | 4.24 | (Ref) | ||||||
| 3 years | 0.85 | 0.02 | 0.01 | 0.04 | 0.121 | 3.69 | − 0.61 | 0.35 | − 0.05 | 0.084 |
| 5 years | 0.86 | 0.02 | 0.01 | 0.04 | 0.144 | 3.49 | − 0.87 | 0.35 | − 0.07 | 0.012 |
| Bivariate p value | 0.161 | 0.045 | ||||||||
| Age | ||||||||||
| < 50 years | 0.85 | 4.61 | ||||||||
| 50–59 years | 0.85 | − 0.01 | 0.02 | − 0.02 | 0.628 | 4.29 | − 0.22 | 0.43 | − 0.02 | 0.612 |
| 60–69 years | 0.86 | 0.00 | 0.02 | − 0.01 | 0.84 | 3.44 | − 0.72 | 0.45 | − 0.06 | 0.107 |
| 70–79 years | 0.85 | − 0.01 | 0.02 | − 0.02 | 0.548 | 3.11 | − 1.29 | 0.52 | − 0.08 | 0.013 |
| 80 + years | 0.77 | − 0.06 | 0.02 | − 0.07 | 0.013 | 4.61 | − 0.12 | 0.68 | − 0.01 | 0.858 |
| Bivariate p value | 0.005 | < 0.001 | ||||||||
| Sex | ||||||||||
| Male | 0.86 | (Ref) | 3.23 | (Ref) | ||||||
| Female | 0.83 | − 0.02 | 0.01 | − 0.04 | 0.273 | 4.52 | 0.38 | 0.39 | 0.03 | 0.325 |
| Bivariate p value | < 0.001 | < 0.001 | ||||||||
| Information needs | ||||||||||
| No needs | 0.90 | (Ref) | 2.36 | (Ref) | ||||||
| Low needs (1–3) | 0.81 | − 0.07 | 0.01 | − 0.17 | < 0.001 | 4.54 | 1.74 | 0.32 | 0.14 | < 0.001 |
| High needs (4 +) | 0.72 | − 0.17 | 0.02 | − 0.28 | < 0.001 | 8.65 | 5.23 | 0.44 | 0.31 | < 0.001 |
| Bivariate p value | < 0.001 | < 0.001 | ||||||||
| Correlation | Correlation | |||||||||
| Index of relative socio-economic disadvantage (deciles) | 0.10 | 0.01 | 0.00 | 0.06 | 0.036 | − 0.06 | − 0.17 | 0.06 | − 0.08 | 0.002 |
| Bivariate p value | < 0.001 | 0.003 | ||||||||
| Number of longstanding comorbidities | − 0.25 | − 0.05 | 0.01 | − 0.23 | < 0.001 | 0.27 | 1.18 | 0.15 | 0.21 | < 0.001 |
| Bivariate p value | < 0.001 | < 0.001 | ||||||||
^Score standardised and range from 0 to 1. Higher scores indicate better quality of life
^^Possible score range: 0–44 higher scores indicate greater social difficulties
#Multivariate analyses controlled for country of birth, response to treatment and residential location